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Electrographic Seizures in Preterm & Full-Term Neonates:Clin Corr Brain Lesions, Risk for Sequelae
Pediatrics 91:128-134, Scher,M.S.,et al, 1993
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Article Abstract
More preterm neonates had a later onset of seizures(>48 hours of life)than term neonates(53%vs 13%,respectively).Ischemic brain lesions were noted in 23(77%)of 30 of full-term compared with 24(39%)of 62 preterm neonates. Intraventricular hemorrhage with ventriculomegaly or intraparenchymal involvement was seen in 26(45%)of 72 preterm neonates compared with 1(3%) of 30 full-term neonates.Mortality was grater in the preterm than in the term populations,36(58%)of 52,compared with 10(30%)of 30,and a normal outcome was documented in 9(25%)of 36 preterm neonates compared with 12 (60%)of 30 full-term survivors.However,the incidence of surviving preterm neonates epilepsy developed was the same as the full-term survivor group at a mean age of 6 1/2 years.While the electroclinical expression of neonatal seizures occurs in both preterm and full-term populations, clinical correlates,incidence,etiologic factors,and outcome factors differ between the two populations.
 
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